There are many things which make a place famous. The town of Kasauli in Himachal Pradesh is one of the famous places for its Pasteus Institutes- Central Research Institute (CRI) of Kasauli, all over in India. This institute is also known as C R I Kasauli. C R I produces the anti rabies vaccine against mad dog and also treats victims who are suffering from deadly diseases. This institute was established by Sir David Semple in 1904. He was the first director of this institute. CRI also works for the World Health Organization (WHO) that is also very well known organisation, as an immunology and virological research.